New! Web of Knowedge Citation Map

ISI Web of Knowledge has rolled out a Beta version of their Citation Map tool. "A Citation Map is a graphical representation that shows the citation relationships (cited references and citing articles) between a paper and other papers using various visualization tools and techniques." You can use the tool to easily see who is citing you or see who you are citing. You can customize the interface and organize the results by year, author, title, institution, country, etc.

You must be on a full record page to see the Citation Map option. To see a full record click on a title from your search results page and look for Citation Map under the journal title.

More information and instructions can be found at:
http://cm.isiknowledge.com/support/help/h_citation_map.html

From the Literature: Virtual Colonoscopy

Accuracy of CT Colonography for Detection of Large Adenomas and Cancers

C. Daniel Johnson, M.D., M.M.M., et al

NEJM 2008; 359 (12):1207-1217.

Early detection for colorectal cancer is key, and current recommendations are for men and women to be screened regularly beginning at 50 years old. However, for a variety of reasons including cost and discomfort, many patients are not adhering to current guidelines and are not undergoing colonoscopies. This study, which involved 2,600 patients at 15 medical centers, indicates that CT colonographies are about as good (90%) as the standard colonoscopies in detecting adenomas of 10 mm or more in diameter. And while the test is less effective for smaller polyps, the authors suggest that the less invasive nature of this procedure may make it an attractive alternative for low-risk patients.

PubMed Update

National Library of Medicine is working on a PubMed redesign and in the process new features are being tested. These tests may cause you some issues while searching PubMed, read on for a simple solution!

The following features, based on the search query, may be encountered in PubMed in the upcoming weeks:

• Also Try - Searches done by other users on the same topic for you to try.
• More PubMed Articles - Other articles that, based on your search terms, may be of interest.
• Recent Activity - A display of your recent PubMed searches and AbstractPlus views, PubMed Central® searches and Full Text views, Gene database searches and Full Report views.

These resources are being introduced on an experimental basis. They may be made available to a small percentage of users so as to gauge their effectiveness, and may even be presented in different ways in order to see if one format is better than another. Based on what NLM learns they will decide how soon to enable a feature for all users, whether to try a different format, or even to go back to the drawing board.

As a result of these tests, you may have intermittent issues with PubMed losing cookies for your search session. You'll know this happened when you don't see the dukemlib tab above your search results or the DUMCL Online or Stacks buttons on the abstract view. To get your cookies back, simply open a new tab/window or go to the Library's Website and click on MEDLINE to restart PubMed. Don't worry! Your search history will be available from the history tab for 8 hours.

From the Literature

In critical care medicine, it is unlikely that any single study has had the influence to match that of the study by van den Berghe et al of intensive insulin therapy in surgical intensive care patients. Published in 2001, the study reported that targeting normoglycemia in ventilated patients in a surgical intensive care unit (ICU) reduced the risk of in-hospital death by one-third. Although the size of the treatment effect seemed improbable, the underlying concept had face validity as improved glycemic control had been proven beneficial in other patients with severe acute illness. As a result, tight glycemic control in critically ill adults is now recommended by numerous organizations including the American Diabetes Association and the Institute for Healthcare Improvement. In this issue of JAMA, Wiener and colleagues report a meta-analysis of studies examining tight glycemic control in critically ill adults; their conclusions, that tight glycemic control does not significantly reduce in-hospital mortality, may surprise many clinicians.

Benefits and Risks of Tight Glucose Control in Critically Ill Adults: A Meta-analysis
Renda Soylemez Wiener, Daniel C. Wiener, and Robin J. Larson
JAMA. 2008;300(8):933-944.

Tight Glycemic Control in Critically Ill Adults (Editorial)
Simon Finfer and Anthony Delaney
JAMA. 2008;300(8):963-965.