From the Literature: PCI vs. CABG
Percutaneous Coronary Intervention versus Coronary-Artery Bypass Grafting for Severe Coronary Artery Disease
In the international SYNTAX trial, 1800 patients with three-vessel or left main coronary artery disease were randomly assigned to either revascularization with coronary-artery bypass grafting (CABG) or percutaneous coronary intervention involving drug-eluting stents. The need for repeat revascularization was significantly lower with CABG, but the risk of stroke was significantly higher — a tradeoff that must be considered in making clinical decisions regarding patients with advanced coronary disease. (summary courtesy of NEJM)
The newly published trial has received a fair amount of press because of it's timing: a provision in the new stimulus bill requires more comparisons of treatments' effectiveness.
Serruys, et al for the SYNTAX Investigators
Published at www.nejm.org February 18, 2009 (10.1056/NEJMoa0804626)
Published at www.nejm.org February 18, 2009 (10.1056/NEJMoa0804626)
In the international SYNTAX trial, 1800 patients with three-vessel or left main coronary artery disease were randomly assigned to either revascularization with coronary-artery bypass grafting (CABG) or percutaneous coronary intervention involving drug-eluting stents. The need for repeat revascularization was significantly lower with CABG, but the risk of stroke was significantly higher — a tradeoff that must be considered in making clinical decisions regarding patients with advanced coronary disease. (summary courtesy of NEJM)
The newly published trial has received a fair amount of press because of it's timing: a provision in the new stimulus bill requires more comparisons of treatments' effectiveness.
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