- EBM Calculators/Prediction rules
- Nomogram
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EBM Calculator
From Mount Sinai Hospital, University of Toronto, the EBM Calculator is designed to calculate relevant statistics for Diagnostic
studies, Prospective Studies, Case Control Studies, and Randomized
Control Trials (RCT). This is a palm version of the Stats Calculator.
Web-based version of the
EBM Calculator.
- Interactive Nomogram
Works best with Internet Explorer.
- UBC Clinical Significance Calculator
From the Department of Health Care and Epidemiology at the University of British Columbia, these sites provide web-based
calculators for sensitivity, specificity, likelihood ratios, and predictive values of diagnostic tests and
absolute risk reduction, relative risk reduction, odds ratio, and numbers needed to treat for therapy studies.
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Clinical Prediction Guides
Clinical prediction guides published in Evidence Based Medicine (BMJ).
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Clinical Prediction rules and Calculators
Mount Sinai School of Medicine.
- Diagnostic Test Calculator
This calculator can determine diagnostic test characteristics (sensitivity, specificity,
likelihood ratios) and/or determine the post-test probability of disease given given
the pre-test probability and test characteristics. Given sample sizes, confidence
intervals are also computed.
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EBM and Decision Tools
From Alan Schwartz of the Department of Medical Education at the University of Illinois at
Chicago. Provides links to decision-making tools and exercises used for
evidence-based medicine or medical decision making. Includes an interactive diagnostic
calculator, a NNT calculator and several exercises for teaching.
- EBM Concepts
From the Medical University of South Carolina, Introduction to Clinical Reasoning page, this site
includes a brief explanation of 2 X 2 Tables, Odds Ratio vs. Relative Risk, p value and 95%
Confidence Intervals, Threshold Decision Making, kappa, and Sensitivity, Specificity, and
Positive Predictive Value.
- Number Needed to Treat?
Dr. Cates' EBM Website. Good visual representation of NNT and Odds ratios. Additional teaching
materials for EBM calculations.
- Online Clinical Calculator
From the Division of Internal Medicine at the Medical College of Wisconsin, this site provides
access to Bayesian Analysis tools, as well as other clinical formulas.
- Effect Size
How to calculate effect sizes from published research articles: A simplified methodology. Provided by
Work-Learning Research is a company that works in the learning-and-performance field, bringing
research knowledge to practice and practicality to research. (Recommendation from Dr. Grace Thrall)
- Simple Interactive Statistical Analysis

SISA allows you to do statistical analysis directly on the Internet. Click on one of the procedures,
fill in the form, click the button, and the analysis will take place on the spot. Study the user friendly
guides to statistical procedures to see what procedure is appropriate for your problem.
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